---
title: 'The $2.6M Female Health Experiment'
source: 'https://youtube.com/watch?v=iuRr_5j9qkY'
video_id: 'iuRr_5j9qkY'
date: 2026-08-21
duration_sec: 401
channel: 'Bryan Johnson'
---

# The $2.6M Female Health Experiment

> Source: [The $2.6M Female Health Experiment](https://youtube.com/watch?v=iuRr_5j9qkY)

## Summary

The video introduces a groundbreaking $2.6 million experiment to measure the female body in unprecedented detail, tracking 1,900 biomarkers across 16 biological systems. Kate Tolo becomes the subject, undergoing daily measurements to understand the female physiology, which has been historically understudied. The project highlights the challenges and disparities in measuring women's health compared to men.

### Key Points

- **Experiment Scale** [00:44] — The experiment will track 1,900 biomarkers, 16 biological systems, 14.8 million data points, and use over 50 devices, costing $2.6 million annually.
- **Kate's Role** [01:28] — Kate Tolo is the subject, with a protocol developed in 90 days, involving daily tasks and measurements across her menstrual cycle.
- **Gender Disparity in Devices** [03:21] — The female arousal monitor is a large, complex device compared to the male version, illustrating the lack of ready-made tools for female measurement.
- **Scientific Gap** [05:18] — The project aims to address the lack of data on female health, serving as an entry point to broader understanding.
- **Human Challenges** [04:24] — The experiment reveals practical challenges and emotional aspects, with Kate humorously noting the difficulty of the protocol.

## Transcript

team and I have measured almost everything there is to measure. But my personal experiments have always had one major limitation. Me. [music] Everything we've done has come from a
single male subject. Women experience dramatically different biological changes across every month, every life stage, and almost every system of the body. So this year, we're beginning our most ambitious experiment yet.
Kate Tolo is about to become the most measured female in history. That's an awkward leaf. [laughter] She's going to spend the next several months doing exactly the same thing every day while we measure hundreds of
biomarkers across every phase of her menstrual cycle. In summary, this menstrual cycle. In summary, this experiment will cover 1,900 biomarkers, experiment will cover 1,900 biomarkers, 16 biological systems, 14.8 8 million
data points over 50 different devices. The annual cost $2.6 million. >> My entire apartment got redone. This doesn't fit in here. [laughter]
>> Watching someone else do this abide with me is very different than doing it yourself. Yeah, it's a lot. >> There's 100 things like I'm not even so much. >> Kate, how are you feeling about this?
mode for the last 4 months and I'm finally ready to take it on. >> This has been a really big lift. I mean, it took 5 years and a team of doctors to build out my protocol and we've done yours in 90 days.
>> One of my favorite moments of this whole experience was revealing my longevity clinic to you. This doesn't fit in here. Everything's fine. [laughter]
Something just fell in there. You need to check if someone got injured. >> You've seen me like [music] oscillating between feeling not ready, ready, panicked, joy, excited, and then I feel like I'm finally ready. Look at my
>> It's so formal with the clipboard. You can see how beautifully designed this and I have nothing of the sort. It's all [music] in my head. Every single second [music] in my head. Every single second is accounted for and I have become an
experiment that is being observed at every moment. I have [music] one, two, days. >> She has in a given day 100 plus [music] >> She has in a given day 100 plus [music] things to do.
your time to say how can you get through those things as fast [music] as possible. Watching someone else do this is very different than doing it yourself. >> Hold your breath.
>> The first thing I do when I wake up is I'm in bed and I have my little nook set >> I obviously have to take out my techno tampon. Come have a look at this device. [music] So, I actually sleep with this inserted this then taped to my leg using
>> Women [music] have not been able to measure their arousal cycles. And it night just like a man's body. >> But this is Brian's version. Yeah. Of an erection monitor. [music] I don't have like the luxury of small
wireless Bluetooth data offloaded thing. It's this beast. Like it's [music] a very complicated device. >> The level of readiness for the world to measure men versus women is captured in that. The device for a man small, easy,
consistent. For a female a gigantic device, 16 different things to change. So if that kind of captures [music] the entire project of like where the >> Yes, [music]
measure women in a rigorous way according to our current scientific standards for randomized controlled trials. So you can start to see just how difficult this gets to put into practice. [music] When I masking taped
just masking tape. It's not a good >> Do you have a Oh. Oh no. What is it? [laughter] Oh no. Oh no. >> But I was like I didn't want to put because I didn't want to cut off my circulation. And then I woke up in the
morning and this was obviously we need to get this replaced. >> Yeah, it's a lot. There's hundred things like this, >> you know, and like no, nobody's going to be able to know besides me, like the
>> Yeah. >> At the end of the day, once I start, >> Yeah. Given [music] the number of things that Kate is doing, I feel very empathetic to a female's experience. Even just like in very practical things
like how well quantified are females relative to men, not as much. How much data is there on females relative to men? Not as much. Yeah, it's really >> Yeah, it's okay. It's okay. I I understand.
>> Do you know why you're so excited about the female experiment? I feel like you got your hands into it and then you were like, "Wo, there's this whole other >> It's It's very sore. >> We talk about adventurous things like
things, but like what about understanding the female body? Why isn't that a gigantic ambition for society? Man, that's a lot. That alone is a lot,
>> You should be nice. >> No, it's true. I would. It's significant. I I don't do that. Now, a lot of people will say like this is just Kate. It's a limited view. But you know what? It's an entry point to this larger
female body? And given the number of things that Kate is doing, I think it's possible we don't really have good intuitions about the female body. >> Do you want to come try a vibration plate? Abide
plate? Abide with me. >> Well, that was [music] pretty cool. Well, thanks for showing me around and
you know this is fun. Can I sleep over? >> Right. I would love that. Well, remember of sleep in the same bed as you. [laughter] If I complete this protocol, get three nights in the [music] same bed as you.
>> You can tell he didn't want to do it, but he's like, "Come on, do it. It will but he's like, "Come on, do it. It will be an experiment. [laughter]