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Science of Muscle Growth, Increasing Strength & Muscular Recovery

Published May 31, 2021 Transcribed Jul 1, 2026 A Andrew Huberman
Intermediate 62 min read For: Fitness enthusiasts, athletes, and anyone interested in the science behind muscle growth, strength training, and recovery.
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AI Summary

This episode of the Huberman Lab Podcast, hosted by Dr. Andrew Huberman, explores the science of muscle, focusing on the critical connection between the nervous system and muscle tissue. It covers how neurons control muscle, the role of lactate in exercise, and provides science-based protocols for muscle hypertrophy, strength, and recovery. The episode aims to give listeners a deep understanding of how to optimize their neuromuscular system for better health, performance, and longevity.

[6:30]
Brain's Purpose is Movement

The whole reason for having a brain is to move. The brain controls movement through upper motor neurons, lower motor neurons, and central pattern generators.

[23:59]
Lactate is a Hero Molecule

Lactate is not a waste product; it buffers acidity, acts as a fuel, and serves as a hormonal signal to the heart, liver, and brain.

[35:30]
Henneman Size Principle

The Henneman Size Principle states that motor units are recruited from low to high threshold. You don't need heavy weights to recruit high-threshold units; working in the 30-80% of 1RM range is effective.

[40:33]
Three Stimuli for Muscle Change

The three stimuli for muscle change are stress, tension, and damage. Muscle growth (hypertrophy) occurs when myosin filaments get thicker.

[57:55]
Optimal Training Volume

For most people, 5 to 15 sets per muscle group per week, in the 30-80% of 1RM range, is effective for improving muscle strength and size.

[87:06]
CO2 Tolerance Test for Recovery

The CO2 tolerance test is a zero-cost, objective measure of nervous system recovery. A slow exhale time (over 60 seconds) indicates good recovery.

[95:49]
Cold and NSAIDs Blunt Gains

Using ice baths or anti-inflammatory drugs within four hours after resistance training can blunt the inflammatory signals needed for muscle growth and adaptation.

[105:03]
Effective Supplements: Creatine & Beta-Alanine

Creatine (3-15g/day depending on body weight) is well-supported to increase power output, reduce fatigue, and improve hydration. Beta-alanine (2-5g/day) improves muscular endurance for 60-242 second activities.

[112:46]
Leucine for Muscle Protein Synthesis

Ingesting 700-3000 mg of the essential amino acid leucine per meal supports muscle protein synthesis and repair.

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95% Legit

"The title accurately reflects the core content: the science of muscle growth, strength, and recovery, with a strong emphasis on the nervous system."

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Tutorial Checklist

1 87:06 Perform the CO2 tolerance test first thing in the morning: take 4 deep breaths (inhale nose, exhale mouth), then on the 5th inhale, fill lungs completely and exhale as slowly as possible. Measure the exhale time.
2 89:30 Interpret your CO2 tolerance test result: if exhale time is under 25 seconds, you are not recovered. 30-60 seconds is the green zone. Over 60 seconds means you are ready to train.
3 52:51 Determine your one-rep max (1RM) for a given exercise, or estimate it. Then, for hypertrophy and strength, work in the 30% to 80% of your 1RM range.
4 57:55 Perform 5 to 15 sets per muscle group per week. For maintenance, aim for 5 sets. For improvement, aim for 10-15 sets. Distribute these sets across 1-2 sessions per week.
5 53:50 Take each set close to failure (where you cannot perform another rep in good form). About 10% of your sets should be taken to actual muscular failure.
6 69:00 For hypertrophy, focus on isolating the target muscle. Use pre-exhaustion (e.g., leg extensions before squats) and consider hard contractions (flexing) between sets.
7 64:08 For strength and explosiveness, focus on moving the weight as fast as safely possible, especially with moderate to heavy loads (60-75% of 1RM). Avoid going to failure.
8 95:49 Avoid using ice baths or taking anti-inflammatory drugs (NSAIDs) within 4 hours after resistance training, as they can blunt muscle growth signals.
9 105:03 Consider supplementing with creatine (3-15g/day depending on body weight) and beta-alanine (2-5g/day) to enhance performance, as supported by research.
10 112:46 Ensure adequate intake of the amino acid leucine (700-3000 mg per meal) to support muscle protein synthesis, ideally from high-quality protein sources.

Study Flashcards (10)

What is the chemical released by motor neurons that causes muscles to contract?

easy Click to reveal answer

Acetylcholine.

14:08

What principle states that motor units are recruited from low threshold to high threshold?

medium Click to reveal answer

The Henneman Size Principle.

35:30

What molecule is produced during anaerobic metabolism and acts as a buffer, fuel, and hormonal signal?

medium Click to reveal answer

Lactate.

23:59

What are the three major stimuli for changing muscle?

hard Click to reveal answer

Stress, tension, and damage.

40:33

What percentage of your one-rep maximum is the most beneficial range for muscle hypertrophy and strength?

medium Click to reveal answer

30% to 80% of your one-rep maximum.

52:51

How many sets per muscle group per week are recommended for most people to improve muscle?

hard Click to reveal answer

5 to 15 sets per muscle group per week.

57:55

What is the name of the zero-cost test to measure nervous system recovery?

hard Click to reveal answer

The carbon dioxide (CO2) tolerance test.

87:06

Why should you avoid ice baths immediately after resistance training?

medium Click to reveal answer

It can interfere with the inflammatory signals needed for muscle repair and growth.

95:49

What essential amino acid is particularly important for supporting muscle protein synthesis?

medium Click to reveal answer

Leucine.

112:46

What supplement is well-supported by research to increase power output and reduce fatigue?

easy Click to reveal answer

Creatine.

105:03

💡 Key Takeaways

💡

Brain's Purpose is Movement

Reframes the purpose of the brain from thinking to controlling movement, highlighting the fundamental role of the neuromuscular system.

6:30
📊

Lactate is a Hero Molecule

Corrects the common misconception that lactate (lactic acid) is bad, explaining its roles as a buffer, fuel, and beneficial hormonal signal.

23:59
🔧

CO2 Tolerance Test for Recovery

Provides a simple, zero-cost, objective test to measure nervous system recovery, which is more actionable than subjective feelings.

87:06
⚖️

Henneman Size Principle

Explains the fundamental principle of motor unit recruitment, which is key to understanding how to train for strength vs. hypertrophy.

35:30
💡

Cold After Training Blunts Gains

Challenges the common practice of using ice baths for recovery, explaining that it can interfere with the inflammatory process needed for muscle adaptation.

95:49

✂️ Creator Tools: Viral Hooks

AI-generated clip ideas for Shorts based on the transcript

The Truth About Lactic Acid (Myth Busted)

36s

Corrects a common misconception that lactic acid causes muscle burn, offering a science-backed perspective that challenges popular fitness beliefs.

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[00:00] - [Andrew Huberman] Welcome

[00:02] where we discuss science

[00:04] for everyday life.

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[02:46] That's what optimizes

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[02:50] Then in the evening I shift over

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[02:54] That's what allows me to sleep very well.

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[03:01] Conventionally raised animals

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[04:06] Today's episode is also

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[05:29] Today's episode of the Huberman

[05:31] and final episode in this month

[05:33] which is all about skills

[05:37] Now, in a previous episode,

[05:41] in particular neuroscience-based tools

[05:43] for accelerating fat loss.

[05:46] Previous to that, we talked about ways

[05:48] to improve skill learning, motor movements

[05:50] which also included things like music

[05:53] and piano playing not

[05:56] And we've also been

[05:59] of physical performance

[06:02] Today I want to talk about something

[06:03] that is vitally important for

[06:07] but for your entire life and

[06:11] and that's muscle.

[06:13] Now, many of you, when

[06:15] think muscle growth and

[06:18] And while we will touch

[06:20] muscle growth today, and

[06:23] to enhance hypertrophy,

[06:27] about muscle as it relates

[06:30] And I can't emphasize this enough

[06:33] the whole reason why you have a brain is

[06:36] so that you can move.

[06:38] And one of the things that's

[06:41] about the human brain,

[06:44] all sorts of different kinds of movement,

[06:46] different speeds of movement,

[06:48] movement of different durations.

[06:50] We can train our

[06:54] and heavier objects or we

[06:56] to take us further and

[06:59] We can also build smoothness

[07:03] smoothness of movement as

[07:07] suppleness of movement.

[07:09] All of that is governed

[07:13] between the nervous system, neurons

[07:16] and their connections to muscle.

[07:19] So when you hear the science of muscle

[07:21] and muscle hypertrophy,

[07:23] I'm not interested in building muscle

[07:25] but muscle does many critical things.

[07:28] It's important for movement.

[07:30] It's important for metabolism.

[07:32] The more muscle you have

[07:36] but the quality of muscle,

[07:39] the higher your metabolism is,

[07:41] and indeed the healthier you are.

[07:44] It turns out that jumping ability

[07:47] and ability to stand up quickly

[07:49] and to get up off the floor quickly

[07:51] is one of the most

[07:54] and biological aging and no

[07:57] by the brain to muscle connection.

[08:00] In addition, muscle and

[08:05] and we don't talk about posture enough.

[08:08] We all have been told we

[08:10] or stand up straight, but

[08:14] for how the rest of our body works.

[08:17] It's vital to how we breathe.

[08:19] It's actually even vital to

[08:23] So we're going to talk about

[08:26] We also are going to talk about muscle

[08:28] as it relates to aesthetic things.

[08:30] Now, these are all linked.

[08:32] Muscle for metabolism,

[08:35] of course are linked, right?

[08:36] As our posture changes,

[08:38] As our posture and aesthetic

[08:42] And as we improve muscle quality

[08:45] whether or not that's

[08:48] that changes the way

[08:51] not just our nervous system

[08:54] but our immune system and the

[08:57] So today, as always we're going to talk

[08:59] a little bit of mechanism.

[09:01] I'm going to explain how

[09:04] and then we're going to

[09:08] how muscle uses energy.

[09:09] I promise to make all of this very simple.

[09:11] I'm actually going to keep it very brief

[09:14] probably about 10 minutes total.

[09:16] And by the end of that 10

[09:19] about the neuromuscular connection,

[09:21] how your brain and nervous

[09:23] and how those muscles work.

[09:25] Then we are going to talk

[09:29] and can change how they use energy

[09:32] for sake of getting stronger, if you like

[09:35] for also increasing the size

[09:38] and for improving endurance as

[09:43] and how you move generally.

[09:45] We will touch on some nutritional themes

[09:48] and how that relates

[09:50] a specific amino acid that

[09:52] if it's available in your

[09:55] and at sufficient levels,

[09:58] and improve the quality of muscle.

[10:01] And we'll talk about

[10:04] as well as of course, supplementation

[10:07] and things that can enhance

[10:09] neuromuscular performance overall.

[10:12] We are also going to talk about recovery.

[10:14] Recovery as everybody knows,

[10:18] That's when neurons get

[10:23] that's when muscle grows,

[10:24] that's when muscle gets more flexible.

[10:27] None of that actually

[10:29] It happens after training and

[10:32] about how to optimize

[10:35] whether or not you are recovered

[10:38] for another neuromuscular

[10:41] So we'll talk about that as well.

[10:43] Today is going to have a lot of protocols

[10:46] and you're going to come away

[10:48] about how you move, how you work

[10:49] in these incredible organs

[10:54] and the musculature, the

[10:58] Before we dive into today's topic,

[11:00] I want to just take about three minutes

[11:03] and cover some essential

[11:07] In the previous episode,

[11:10] Talked about shiver induced fat loss.

[11:12] We talked about neat non-exercise

[11:16] for increasing caloric

[11:19] And we talked about how

[11:23] to enhance fat loss.

[11:25] I described a protocol

[11:28] of some sort, whether or not

[11:31] some form of cold could

[11:34] if you have access to

[11:37] and then getting out, not

[11:41] but allowing that cold to evaporate

[11:43] off you and continuing to shiver

[11:44] and then getting back into

[11:46] of water or stream or shower, et cetera.

[11:50] All of that is described

[11:51] in a beautifully illustrated protocol

[11:54] that I didn't illustrate.

[11:55] That's why it's beautifully illustrated

[11:57] at the coldplunge.com.

[11:59] They've made that protocol for you

[12:02] and they've made it available

[12:05] So there's no obligation

[12:07] You can go to the coldplunge.com.

[12:10] There's a little tab that says protocols

[12:11] and you can download that

[12:13] I don't know who exactly illustrated it,

[12:16] and you can come away with a PDF

[12:17] of what I described in

[12:18] So I just want to make sure

[12:20] that you are aware of that resource.

[12:22] The other announcement

[12:24] many of you have asked how you

[12:27] And there's a very straightforward

[12:31] And that's to subscribe

[12:33] So if you go to YouTube,

[12:35] if you're not already

[12:37] hits the Subscribe button

[12:40] to get the word out more

[12:43] And we thank you for your support.

[12:45] Most people, when they

[12:47] they just think about strength.

[12:49] But of course muscles are

[12:53] They are involved in speaking,

[12:54] they're involved in

[12:56] they're involved in lifting

[13:00] They are absolutely essential

[13:03] for maintaining how we breathe.

[13:05] They're absolutely essential

[13:09] and for skills of any kind.

[13:11] So when we think about muscle,

[13:14] we don't just want to think about muscle

[13:16] the meat that is muscle, but

[13:20] And no surprise what controls

[13:25] The nervous system does that

[13:26] through three main nodes of

[13:29] And I've talked about these

[13:32] So I will keep this very brief.

[13:34] Basically, we have upper motor

[13:38] So those are in our skull

[13:40] and those are involved

[13:42] So if I decide that I'm

[13:44] up and put it down, which

[13:46] my upper motor neurons were involved

[13:48] in generating that movement.

[13:49] Those upper motor

[13:52] to my spinal cord where there

[13:56] One are the lower motor neurons

[13:58] and those lower motor

[14:01] that we call axons out to our muscles

[14:04] and cause those muscles to contract.

[14:06] They do that by dumping

[14:08] In fact, the chemical is acetylcholine.

[14:12] I've talked before about

[14:15] which is vitally important for focus

[14:17] and actually can gait neuroplasticity,

[14:19] the brain's ability to change

[14:23] But in the neuromuscular system,

[14:25] acetylcholine released from

[14:28] the only way that muscles can contract.

[14:33] Now, there's another category of neurons

[14:35] in the spinal cord called

[14:37] or CPGs.

[14:39] And those are involved

[14:41] Anytime we're walking or doing something

[14:44] where we don't have to think about it

[14:45] to do it deliberately, it's

[14:48] that central pattern

[14:51] Anytime we're doing

[14:53] the top-down control as we call it,

[14:56] from the upper motor neurons comes in

[14:57] and takes control of that system.

[15:00] So it's really simple.

[15:00] You've only got three ingredients.

[15:02] You've got the upper motor

[15:04] and for rhythmic movements

[15:06] you've also got the

[15:08] So it's a terrifically

[15:11] but what we're going to focus on today is

[15:15] how that system can control muscle

[15:18] in ways that make that system better.

[15:21] Now, when I say better, I

[15:24] If your goal is to build larger muscles,

[15:27] there's a way to use your nervous system

[15:30] to trigger hypertrophy

[15:34] of those muscles.

[15:35] And it is indeed controlled

[15:38] So you can forget the idea

[15:41] or that muscles grow in

[15:43] that's just happening within the muscle,

[15:45] it's the nerve to muscle connection

[15:47] that actually creates hypertrophy.

[15:50] I'll talk exactly about how

[15:53] In addition, if you want

[15:55] or improve flexibility or

[15:59] that is all accomplished by the way

[16:02] that the nervous system

[16:05] And so what that means is

[16:08] are we going to take control

[16:10] the central pattern generators,

[16:13] or all three in order

[16:17] of how the nervous system controls muscle.

[16:20] So neurophysiology 101.

[16:23] I'll give you one piece of history

[16:24] because it's important to know.

[16:26] Sherrington, who won the Nobel prize

[16:30] called movement, the final common path.

[16:33] Why did he say that?

[16:34] Well, the whole reason for

[16:38] the whole reason for having a brain is

[16:39] so that we can control our

[16:43] That is one of the reasons,

[16:47] why the human brain is so large.

[16:50] You might think, oh it's

[16:52] and for creativity.

[16:53] Ah, no when you look at

[16:56] in the brain that's devoted

[16:59] it's mainly vision, our ability to see

[17:03] and movement, our ability to engage

[17:05] in lots of different kinds of movements.

[17:07] Slow movements, fast movements,

[17:10] Other animals don't have that ability

[17:14] because they don't have

[17:17] They don't have the neural

[17:20] They have neuromuscular junctions.

[17:22] They have central pattern generators

[17:23] what they don't have

[17:24] are these incredible upper motor neurons

[17:26] that can direct activity the

[17:30] So we can all feel blessed

[17:32] And today I'm going to teach

[17:35] toward particular end points.

[17:37] So if we decide that we are

[17:40] in some particular movement of any kind.

[17:42] Whether or not it's a

[17:44] or whether it's a yoga movement

[17:46] or simply picking up

[17:49] we are engaging flexors and extensors

[17:52] and our body is covered with

[17:55] So for instance, our bicep is a flexor

[17:57] and our tricep is an extensor.

[17:59] Those are what are called

[18:01] They move the limbs in

[18:04] So if you bring your wrist

[18:06] that's flection using your bicep.

[18:08] If you move your wrist further

[18:11] that's extension, using your tricep.

[18:13] And without getting into a lot of detail

[18:15] the way that the nerves and

[18:19] make it such that when

[18:22] when the nerve dumps

[18:26] onto the muscle to activate the biceps,

[18:28] the triceps is inhibited.

[18:31] It's prevented from engaging.

[18:34] There are ways to bypass this

[18:36] but that's the typical mode of action.

[18:39] The converse is also true when

[18:44] when we move our wrist

[18:46] our bicep is inhibited.

[18:48] And we have flexors like

[18:51] And we have extensors in our lower back.

[18:54] Many of you probably know this

[18:55] but some of you probably

[18:57] has flexors to move basically

[19:01] And it has, those are your

[19:04] And you have extensors that

[19:08] like looking up toward the ceiling.

[19:09] And those are your extensors.

[19:11] You have other muscles that

[19:13] and things of that sort

[19:14] but those movements of

[19:17] and the fact that they are

[19:18] what we call reciprocally

[19:22] you hear different language around this

[19:23] is characteristic of most

[19:29] So hamstring and quadriceps,

[19:32] closer back towards the glutes.

[19:35] Basically it's lifting your heel up

[19:38] which is almost always

[19:40] Whereas your quadriceps is the extensor

[19:43] opposite to the hamstrings.

[19:44] So you get the idea.

[19:45] So there's flexors and extensors

[19:47] and it's the neurons that

[19:50] and extensors that allow us

[19:53] So, now you have heard a

[19:57] in its simplest form, but I

[19:59] I want to get just briefly, just briefly

[20:03] into some of the underlying metabolism

[20:05] of how muscles use and create energy.

[20:08] Because in doing that, we

[20:10] to understand all the

[20:13] how to optimize the neuromuscular system

[20:15] for your particular goals.

[20:16] So in the previous episode about fat loss,

[20:18] we talked about lipolysis.

[20:20] The breakdown of fat into fatty acids

[20:22] so it can be used as fuel.

[20:24] And it ended in a step where we got ATP,

[20:27] which is the bottleneck

[20:30] for all energy producing

[20:35] There are other ways but basically ATP

[20:37] is the key element there.

[20:39] Now with muscles, they don't

[20:43] what they are going to function

[20:46] and their ability to do

[20:49] in any way that we want to,

[20:51] is based on a process of glycolysis,

[20:53] the breakdown of things like glycogen

[20:57] and glucose into energy.

[20:59] And it's a very simple process.

[21:01] You don't have to know any chemistry.

[21:03] So if I say the words carbon or hydrogen

[21:05] or something like that, don't freak out.

[21:06] You don't have to

[21:09] But basically what

[21:12] available sugar resource

[21:17] And that's glucose.

[21:18] And that glucose has six carbons

[21:25] That can be broken down into

[21:31] All right.

[21:32] So basically you take

[21:34] into these two little batches of carbons

[21:37] that we call pyruvate.

[21:38] So six divided by two is three.

[21:39] So you get three and three pyruvate.

[21:41] And that generates a

[21:44] but just a little bit.

[21:46] Now, if there's oxygen available,

[21:49] if there's sufficient oxygen there,

[21:52] what can happen is that

[21:56] to the mitochondria and

[21:59] that you probably don't

[22:01] like the electron transport

[22:05] What happens is it's broken

[22:10] which has a lot of ATP.

[22:12] So the only things you need to know,

[22:13] the only things you need

[22:15] is that glucose and glycogen

[22:19] You a little bit of energy from that.

[22:20] And when I say energy, I

[22:23] It's fuel, literally just gets burned up.

[22:26] But if there's oxygen

[22:29] then within the mitochondria,

[22:34] which is a lot of ATP.

[22:36] Now, what does this mean?

[22:37] This means that movement of muscle

[22:40] is metabolically expensive

[22:42] to other tissues compared

[22:46] compared to almost all other

[22:49] muscle is the most metabolically demanding

[22:52] which is why people who

[22:55] to adipose tissue to

[22:58] and they're more of a furnace.

[23:00] They just kind of burn that up.

[23:02] So even if you didn't understand

[23:05] what you probably did hear,

[23:08] is that if you have oxygen

[23:12] from this fuel source that

[23:16] But what if there isn't oxygen around?

[23:18] And what is that like?

[23:20] Well, you've experienced that.

[23:22] I'm not talking about

[23:24] I'm talking about oxygen in the muscle.

[23:26] So if you've ever carried

[23:29] or you're carrying heavy

[23:32] or you're exercising particularly hard

[23:34] and you felt the burn, well, that burning

[23:37] which most people think is

[23:43] by which pyruvate, which as I said before

[23:45] normally could be converted

[23:48] well, if there's not enough oxygen

[23:50] 'cause that muscle is

[23:53] what ends up happening is that

[23:54] a hydrogen molecule comes in there

[23:57] and you get something called lactate.

[23:59] So believe it or not, humans

[24:01] That's another species, we make lactate.

[24:05] And we hear that lactate is bad.

[24:07] We need to buffer the

[24:11] That lactic acid and

[24:14] for performing as well

[24:17] or going as far as we possibly could

[24:20] in an endurance event.

[24:22] Guess what, that's not true at all.

[24:24] Lactate has three functions,

[24:25] all of which are really

[24:28] First of all, it's a

[24:32] You don't want muscle to get too acidic

[24:34] because it can't function.

[24:35] You don't want any body

[24:37] So that burn that you feel is

[24:42] and lactate what most

[24:45] but again, we don't make lactic acid.

[24:46] Lactate is there to buffer that

[24:49] to reduce the amount of burn.

[24:51] So, most people have

[24:54] So when you feel that burn

[24:57] that is lactate that's

[25:02] to suppress acidity.

[25:04] It's also a fuel.

[25:06] When you feel that burn,

[25:08] lactate is shuttled to

[25:11] and there's an actual fuel burning process

[25:14] where in the absence of oxygen

[25:16] you can continue to generate

[25:19] Now, this is informative

[25:21] that burning that acidity that we feel

[25:24] can inhibit the way that our muscles work

[25:27] but that lactate comes

[25:29] to continue to function.

[25:31] So we'll talk a little bit more about

[25:33] what this whole lactate

[25:36] but it's a really important process.

[25:38] And it's amazing to me that

[25:40] in exactly the incorrect way.

[25:42] They think a lactic acid

[25:45] No, it reveals a number

[25:47] are going on with this

[25:50] which can reduce acidity, reduce the burn

[25:53] as well as act as a fuel.

[25:55] Now, here's where it

[25:58] And if you don't have enough

[26:01] based on all the information out there

[26:03] about how it'll make you live longer

[26:05] and make your heart better, et cetera,

[26:07] here's a reason that regardless

[26:10] of what kind of exercise you do,

[26:12] if it's weight training, or

[26:15] that every once in a while,

[26:19] you should exercise to

[26:22] where you start to feel

[26:26] The reason for that is

[26:31] to the site of the burn, so to speak,

[26:34] and it acts as a hormonal

[26:37] of the body in a very positive way.

[26:41] As you may recall, from

[26:43] of the Huberman Lab

[26:45] what a hormone is and how it works.

[26:47] We have lots of different

[26:49] but hormones are chemicals that

[26:52] in the body and travel,

[26:55] of other organs of the body.

[26:57] So when I say that lactate

[27:03] what I mean is that it's in a

[27:06] that are outside of the muscle.

[27:09] And basically it can send signals

[27:13] to the heart, to the

[27:16] and it can have effects

[27:18] and the brain that are very positive.

[27:21] So just to zoom out for a second

[27:23] I promise we won't get any

[27:25] We will get into tools and protocols

[27:27] that are really straightforward

[27:28] but what I'm telling you is that

[27:31] if you feel a burn from a

[27:37] that burn is going to be buffered

[27:40] by this molecule we call lactate.

[27:42] Lactate will then provide additional fuel

[27:44] for additional work.

[27:46] So this is a good incentive

[27:48] to "Work through the burn."

[27:51] That burn acts as a beacon to the lactate

[27:56] which comes in and allows

[27:58] It's not a signal to stop necessarily.

[28:00] I mean, stop if you're

[28:02] but it's a signal that

[28:05] and allow you to continue to do work.

[28:07] And it can act as a hormonal signal.

[28:10] Lactate can then travel to the heart

[28:14] and to the liver and to the brain

[28:16] and can enhance their

[28:18] not just in those moments,

[28:19] but in the period of time that follows.

[28:22] So many people are curious

[28:25] to make their brain better.

[28:27] That's one of the most

[28:29] What I'm telling you is that

[28:34] by engaging the so-called burn

[28:36] which is at a different

[28:39] your hill run will be

[28:41] to generate the burn,

[28:43] but provided you can do that for about 10%

[28:45] of your workouts or of

[28:49] or activity of any kind, you

[28:54] of this lactate based hormonal signal

[28:56] that can improve the function of neurons.

[29:00] And it does that if you want

[29:02] by improving the function

[29:04] called the astrocytes which

[29:07] Which are very involved in clearance

[29:09] of debris from the brain,

[29:10] they're involved in the

[29:12] connections between neurons in the brain.

[29:14] So put simply, if you are an exerciser

[29:18] if you're doing movement of

[29:20] in allocating some of that

[29:24] brain, heart and liver

[29:29] of scientific data that points to the fact

[29:31] that getting a lactate

[29:34] by engaging this burning

[29:39] for the health of those other tissues.

[29:40] So, as I mentioned that burn is present

[29:43] from lack of oxygen being present.

[29:46] And then the hydrogen comes

[29:49] But this process of

[29:52] of fuel and a positive hormonal

[29:56] occurs only if there's oxygen.

[29:59] So if you feel the burn,

[30:03] on your breathing at that point.

[30:05] That would be the time

[30:07] and try and bring more

[30:10] It's definitely not a

[30:12] And if ever you've run to

[30:15] and then you were exercised

[30:17] or on the bike or whatever,

[30:19] and then you held your breath,

[30:20] it feels much more intense.

[30:22] By breathing you bring lactate to the site

[30:26] and you are able to

[30:30] as a buffer, a fuel,

[30:33] And the reason I brought this up today is

[30:35] because as I mentioned so

[30:38] in using exercise not just for sake

[30:40] of improving physical health

[30:43] but also for enhancing their brain.

[30:46] And there are a lot of

[30:49] to the findings that

[30:53] can increase neurogenesis,

[30:57] Well, the unfortunate news is that

[31:00] while that's true in mice,

[31:01] there is very little evidence

[31:05] from exercise or otherwise in humans.

[31:08] There's a little bit,

[31:09] within the brain, such

[31:11] of the hippocampus, which may be involved

[31:13] in the formation of new

[31:16] the dentate gyrus is definitely involved

[31:17] in the formation of new memories,

[31:19] whether or not the new

[31:21] in humans are involved in new memories.

[31:24] The evidence for that

[31:27] whereas an animals the

[31:30] but most of the data points to the fact

[31:32] that hormonal signals,

[31:36] in the blood during exercise

[31:42] and that those signals are

[31:45] in the number of neurons in

[31:49] That it's more about the

[31:51] between the neurons growth

[31:54] things like IGF-1, there's

[31:56] So if you've heard the

[31:59] of neurons in your brain,

[32:01] And that probably is a good thing, frankly

[32:03] because we always hear

[32:06] as if it's a good thing, but

[32:09] with bringing in entirely new elements.

[32:12] It has a hard time negotiating that

[32:14] and making use of those new elements.

[32:16] We know about this from things

[32:19] where deaf people are given a device

[32:20] where they suddenly can hear.

[32:22] Some people really like that,

[32:24] deaf people really like that

[32:26] Other deaf people find

[32:29] That is hard to take an existing

[32:34] and incorporate a lot of

[32:37] So new neurons, as great as that sounds

[32:39] more neurons, more neurons,

[32:40] it actually might not be the best way

[32:42] for the nervous system to

[32:44] and to promote its own longevity.

[32:46] So when I tell you not such great evidence

[32:50] from new neurons past puberty,

[32:52] that's what the data

[32:55] And I sort of knocked back the data

[32:57] on exercise and neurogenesis,

[32:59] don't let that depress you.

[33:00] If you have dementia in your family,

[33:03] don't translate that into necessarily

[33:06] that you will develop dementia.

[33:08] Understand the exercise

[33:10] for the brain and other

[33:13] but that it's going to be doing it

[33:14] through these hormonal signals.

[33:16] Things like IGF-1, things

[33:20] when you experience

[33:22] And again, you don't want to try

[33:23] and get this feeling of a burn

[33:25] throughout the entire episode of exercise,

[33:28] there'll be far too intense and

[33:31] I don't think it'd be good

[33:33] It's only about 10% of your total effort

[33:36] in any one exercise about

[33:38] that's going to give you

[33:40] So now you know how to

[33:42] of your exercise, 10% in

[33:46] to benefit other tissues

[33:48] namely your heart, your

[33:51] I'd now like to shift our attention

[33:53] to how to use specific aspects

[33:57] to improve muscle

[34:00] as well as improving muscle strength.

[34:03] There are a lot of reasons

[34:05] And I should just mention

[34:09] that getting stronger involves

[34:12] There are ways for muscles to get stronger

[34:14] without getting bigger.

[34:16] However, increasing the size of a muscle

[34:19] almost inevitably increases

[34:22] at least to some degree.

[34:24] Reasons why most everyone should want

[34:26] to get their muscles stronger is that

[34:29] muscles are generally

[34:32] across the lifespan.

[34:33] So when I say getting

[34:35] about being able to move increasing mounts

[34:39] of weight in the gym.

[34:40] Although if that's your goal

[34:41] what I'm about to discuss

[34:44] but rather to offset some of

[34:49] and posture and the ability

[34:53] of movement safely, that occurs as we age.

[34:56] As I mentioned at the

[34:57] we just tend to lose function

[35:01] as we get older.

[35:02] And doing things to offset that

[35:04] has been shown again and

[35:07] for the neuromuscular system

[35:11] for enhancing the strength

[35:14] So there are a lot of reasons

[35:18] that extend far beyond just the desire

[35:20] to increase muscle size

[35:23] of you are interested in

[35:25] but many of you are not.

[35:27] So there's an important

[35:30] called the Henneman size principle.

[35:32] And the Henneman size

[35:35] that we recruit what

[35:40] Motor units are just the connections

[35:41] between nerve and muscle from in a pattern

[35:46] that staircases from low

[35:50] What this means is when you

[35:54] you're going to use the

[35:57] to muscle energy in

[36:00] Likewise, when you pick

[36:03] you're going to use the

[36:06] to muscle connectivity and energy

[36:08] in order to move that object.

[36:10] So it's basically a conservation

[36:14] Now, if you continue to

[36:19] what will happen is you will tend

[36:21] to recruit more and more

[36:24] And that process of

[36:27] more lower motor neurons

[36:29] if you recall from the

[36:31] these lower motor neurons

[36:33] and they actually dump a

[36:36] caused the muscles to contract.

[36:38] As you recruit more and

[36:41] these connections between these

[36:43] lower motor neurons and muscle,

[36:44] that's when you start to

[36:48] That's when you open the

[36:52] for the muscles to get

[36:54] if that's what your goal is.

[36:56] And so the way this process works

[37:00] has been badly misunderstood

[37:02] in the kind of online

[37:05] and bodybuilding, and

[37:08] The Henneman size principle is kind of

[37:10] a foundational principle

[37:14] but many people have come

[37:18] that the way to recruit

[37:21] the ones that are hard to get to

[37:23] is to just use heavy weights.

[37:25] And that's actually not the case

[37:27] as we'll talk about the research supports

[37:30] that weights in a very large

[37:36] of your maximum, anywhere from 30% to 80%.

[37:40] So weights that are not very

[37:44] too heavy can cause

[37:47] between nerve and muscle that lead

[37:49] to muscle strength and muscle hypertrophy.

[37:52] Put differently, heavyweights

[37:57] and strength but they are not required.

[37:59] What one has to do is adhere

[38:01] to a certain number of parameters,

[38:03] just a couple of key variables

[38:06] And if you do that, you can greatly

[38:09] increase muscle hypertrophy, muscle size

[38:12] and or muscle strength if

[38:15] And you don't necessarily

[38:18] in order to do that.

[38:19] Now, I'm sure the power lifters

[38:21] and the people that like to

[38:24] will say, no, if you want to get strong

[38:26] you absolutely have to lift heavy weights.

[38:28] And that might be true if

[38:31] but for most people who are interested

[38:33] in supporting their muscular

[38:37] any age related decline in strength,

[38:39] or in increasing hypertrophy

[38:44] there really isn't a need

[38:45] to lie about the Henneman size principle

[38:48] which many people out there are doing

[38:50] and claiming that you absolutely need

[38:52] to use the heaviest weights possible

[38:53] in order to build strength and muscle.

[38:55] So I'm going to explain all

[38:58] So first of all, let's just

[39:02] and what strength changes

[39:05] We can make this very simple as well.

[39:07] If this were a muscle physiology class

[39:09] we would talk all about myofibrils

[39:12] and sarcomeres and all that stuff.

[39:13] We're not going to do that.

[39:14] That's not the purpose

[39:17] If you're interested in that

[39:18] as well as a lot of the other information

[39:20] that I'm going to discuss in more detail,

[39:23] I highly encourage you to

[39:27] and the writings of Dr. Andy Galpin.

[39:30] He's a PhD and a full professor

[39:33] He's extremely knowledgeable

[39:36] of science-based tools for hypertrophy,

[39:39] how strength and hypertrophy really work.

[39:41] His lab does everything

[39:44] working with athletes and

[39:46] A lot of the information

[39:48] from me in the next 15 minutes or so

[39:50] comes from an extensive

[39:53] that he and his colleagues

[39:56] as folks like Brad Schoenfeld,

[39:59] in this whole space of muscle physiology

[40:01] and from a lengthy conversation

[40:05] Dr. Galpin prior to this episode.

[40:08] So if we want to think

[40:11] we have to ask what is changing

[40:13] when muscles get larger or stronger.

[40:15] And there are really just three ways

[40:17] that muscles can be stimulated to change.

[40:20] So let's review those three ways

[40:21] and talk about what

[40:24] So there are three major stimulate

[40:26] for changing the way that muscle works

[40:29] and making muscles stronger,

[40:33] And those are stress, tension, and damage.

[40:38] Those three things don't

[40:42] but stress of some kind has to exist.

[40:44] Something has to be different

[40:46] in the way that the nerve communicates

[40:48] with the muscle and the way

[40:50] or performs that makes

[40:55] So this is very reminiscent of

[40:58] Something needs to happen.

[41:00] Certain chemicals need to be present.

[41:01] Certain processes need to happen

[41:03] or else a tissue simply

[41:06] But if those processes

[41:09] then the tissue has

[41:13] but to change.

[41:14] So muscles move, as I mentioned

[41:17] because nerves dump

[41:20] but they move because they

[41:24] and actin filaments.

[41:25] And if you want to read up on this,

[41:27] you can look on the internet

[41:29] you can put the sliding filament theory

[41:31] of muscle contraction if you

[41:33] that rabbit hole.

[41:34] It's interesting.

[41:35] You can learn about this in

[41:38] But basically, along

[41:41] you have, what's called myosin.

[41:43] And just think of myosin

[41:46] It's like a bunch of beads and wires

[41:49] that extend across the muscle.

[41:51] I think that's the simplest

[41:53] And the myosin is surrounded

[41:55] by these little beads called actin.

[41:58] The way muscles get bigger is

[42:00] that basically the myosin gets thicker.

[42:04] It's a protein and it gets thicker.

[42:07] So put this in your mind

[42:10] or even if you're watching it on YouTube,

[42:12] the way to think about this

[42:13] and thing and muscles

[42:16] that you're holding a bouquet of balloons,

[42:18] a bunch of balloons by their strings

[42:21] except you're not holding the

[42:23] So the bouquet isn't nicely arranged.

[42:25] It's not like some balloons

[42:28] and you're holding the

[42:30] Imagine that one of the

[42:33] to your hand and other one

[42:35] And so this bouquet is very disorganized.

[42:37] In other words, the string

[42:39] the strings rather

[42:41] are all different lengths.

[42:43] And so the balloons

[42:45] That's essentially what myosin

[42:49] And those strings are what

[42:51] and then the myosin head is the balloon.

[42:56] When you stress a muscle properly,

[42:58] or you give it sufficient tension,

[43:00] or you damage the muscle just enough,

[43:04] there's an adaptive

[43:06] where protein is synthesized.

[43:08] And it's a very specific

[43:11] The myosin gets thicker.

[43:12] In other words, the balloons get bigger.

[43:16] So the way to think about muscle growth

[43:18] and the way to think about

[43:22] that those balloons get bigger

[43:26] Now, the question then should be as always

[43:30] how does that happen?

[43:31] I mean, the muscle doesn't

[43:33] about what's happening

[43:36] The way it happens is

[43:39] to tell the muscle to get stronger.

[43:42] And it does that through what

[43:45] It talks to the muscle

[43:47] It doesn't whisper to it or

[43:49] What it does it release

[43:51] that within the muscle,

[43:53] there are certain

[43:55] that make those balloons

[43:57] the myosin get thicker.

[43:59] So let's talk about the

[44:02] And if already in your

[44:04] oh my goodness, these balloons of muscle

[44:06] are going to get thick,

[44:07] and it's just going to

[44:10] don't worry about that.

[44:11] People invest a ton of time and energy

[44:13] into trying to make their muscles larger.

[44:15] It's actually much harder for people to do

[44:17] than you might think.

[44:19] But I do want to give one

[44:22] an important principle of

[44:24] Everybody has imbalances

[44:32] How well muscles can grow, or how poorly,

[44:35] or how challenging it is

[44:37] Now, many people who are afraid

[44:41] for instance, are afraid

[44:43] But I think the research

[44:46] of pretty much every age should be doing

[44:48] some sort of resistance exercise

[44:50] even if that's body weight exercises

[44:52] in order to offset this

[44:55] in muscle contractile ability,

[44:57] muscle strength, et cetera,

[45:00] There's nothing good about

[45:05] And people who invest the effort

[45:07] into doing resistance

[45:10] whether or not it's with

[45:12] or with body weight,

[45:15] at a whole body level at a systemic level

[45:18] as well as in terms of muscle strength.

[45:21] There is a good predictor of how well

[45:25] or how efficient you will

[45:28] and or if you like the

[45:32] And it has everything to do

[45:34] that are involved in

[45:37] You can actually do this test right now.

[45:39] You can just kind of March

[45:42] and see whether or not you

[45:46] or all of your muscles.

[45:48] So for instance, if you

[45:50] or a you're standing,

[45:52] see whether or not you can

[45:55] just using those upper motor

[45:58] and deliberately

[46:01] If you can contract the calf muscle hard

[46:05] to the point where that

[46:07] like it's starting to cramp

[46:08] like it hurts just a little bit,

[46:10] that can be extremely painful

[46:12] nor is it going to have

[46:15] chances are you have very good

[46:17] upper motor neuron to calf control.

[46:20] And chances are, if you can isolate that

[46:23] what they call the brain

[46:26] and you can contract the muscles

[46:27] to the point where it cramps a little bit,

[46:29] that you hold a decent to high potential

[46:33] to change the strength and

[46:36] if you train it properly.

[46:37] Now, if you have a hard time doing that,

[46:40] chances are you won't be able to do that.

[46:43] If for instance, you

[46:47] Like we all have these

[46:50] The latissimus dorsi muscles,

[46:53] in chin ups and things like that,

[46:53] but their function from a more

[46:58] is to move the elbow back behind the body.

[47:01] So it's not about flexing your bicep.

[47:03] It's about moving your

[47:05] If you can do that, mentally

[47:08] or you can do that physical movement

[47:10] of moving your elbow back behind your body

[47:12] and you can contract that muscle hard,

[47:14] chances are that you have the capacity

[47:16] to enhance the strength and or size

[47:19] of that particular muscle

[47:21] because you have the neural

[47:24] This is a key feature of

[47:27] to appreciate as we begin to talk more

[47:30] about specific protocols.

[47:32] Because everything about

[47:36] about stimulating muscle growth is

[47:39] about generating isolated contractions

[47:42] about challenging specific

[47:48] Whereas with strength, it's

[47:51] as a system moving

[47:54] moving the body.

[47:56] The specific goal of hypertrophy is

[47:59] to isolate specific

[48:02] so that you stimulate the chemical

[48:04] and signaling transduction

[48:06] so that those muscles

[48:09] So there's a critical distinction

[48:11] in terms of getting stronger versus trying

[48:13] to get muscles to be

[48:17] And it has to do with how much

[48:21] Muscle isolation is not

[48:24] It's not something that we normally do.

[48:25] When we walk we don't think,

[48:28] left calf contract.

[48:29] No, you just generate

[48:32] And of course, there's no

[48:34] or larger in response to those movements.

[48:36] Let's say you were to do a

[48:39] of attaching 30 pound

[48:41] And you were to do those movements.

[48:43] Well, if you weren't specifically

[48:46] in each step, there's

[48:49] to take on the bulk of the work.

[48:51] And you would distribute that

[48:54] and other aspects of your musculature.

[48:55] Your whole nervous system

[48:58] It seeks to spread out the effort.

[49:01] So you can nest this as

[49:04] which is if you want to get stronger

[49:06] it's really about moving

[49:10] or increasing the amount

[49:13] Whereas if you're specifically interested

[49:15] in generating hypertrophy,

[49:18] to generate those really hard,

[49:20] almost painful localized

[49:24] Now, of course, how much weight you use

[49:25] in order to generate those contractions

[49:27] will also impact hypertrophy.

[49:29] But I think most people

[49:31] the mind muscle connection.

[49:33] It sounds like a great thing,

[49:34] but it's actually one of

[49:37] if your goal is simply

[49:40] or to become stronger.

[49:42] You want to do the movements

[49:45] but it's the opposite of hypertrophy

[49:48] where with hypertrophy

[49:50] that particular muscle

[49:53] do the majority, if not all the work

[49:56] whereas in moving force loads

[49:58] in trying to generate activity of any kind

[50:02] like lifting a bar, doing

[50:04] those so-called compound

[50:06] of muscle groups.

[50:08] If your goal is to be better at those,

[50:10] you want to avoid isolating

[50:14] Now, I know this probably comes across

[50:16] as a kind of obvious duh,

[50:19] who have spent a lot of time in the gym

[50:22] aimed at getting hypertrophy.

[50:24] But I think most people don't appreciate

[50:25] that it's the nerve to muscle connections

[50:27] and the distinction

[50:30] to muscle connections

[50:33] of nerve to muscle connections,

[50:34] that's vital in determining whether or not

[50:36] you generate hypertrophy isolated nerve

[50:39] to muscle contractions versus strength

[50:41] and offsetting strength loss

[50:44] which would be distributed

[50:47] If ever there was an

[50:49] that was very confused,

[50:53] and almost combative at times,

[50:55] it would be this issue

[50:58] I suppose the only thing

[51:01] of a conversation than that

[51:04] Those seem to be the two most common areas

[51:07] of online battle and the

[51:11] has a lot to say about

[51:13] Again, my sources for

[51:16] are Professor Andy Galpin and colleagues.

[51:19] I know there are other

[51:21] in the field, but I really trust his work.

[51:23] He does very controlled studies.

[51:26] He spent a lot of time in this space

[51:27] and what's really exciting is that

[51:29] in just the last three years or so,

[51:31] there's been a tremendous

[51:34] to come out about the practical

[51:37] in order to maximize the benefits

[51:40] of resistance exercise of any kind.

[51:43] So I'm going to talk about those

[51:44] and I'm going to talk about the research.

[51:46] I will provide some links,

[51:49] in-depth tutorials from

[51:53] of the papers that the

[51:55] to tell you stems from.

[51:58] There's a lot of information saying

[52:00] that you need to move

[52:05] of your one rep maximum

[52:07] for three weeks on and then

[52:09] There are a lot of

[52:12] there are a lot of ways to

[52:16] There's a near infinite number of ways

[52:17] to add up different

[52:20] And what's very clear now

[52:22] from all the literature that's transpired

[52:24] and especially from the literature

[52:27] is that once you know roughly

[52:32] the maximum amount of

[52:36] an exercise with for one repetition

[52:38] in good form, full range of motion,

[52:41] that it's very clear that moving weights

[52:46] or using bands or using

[52:51] in the 30% to 80% of one-rep maximum.

[52:54] That is going to be the

[52:57] in terms of muscle

[52:59] So muscle growth and strength.

[53:01] And there will be a bias

[53:04] that are in the 75%, 80% range

[53:07] or maybe even going above that 85 and 90%,

[53:09] you're going to bias your improvements

[53:12] towards strength gains.

[53:13] This is true.

[53:15] And if you use weights that are in the 30%

[53:17] of your one-repetition

[53:20] and doing many more

[53:23] then you are biasing towards hypertrophy

[53:25] and what some people like

[53:27] But that's a little bit

[53:29] because endurance, we almost

[53:33] to running or swimming or

[53:36] So 30% to 80% of one-repetition maximums,

[53:39] it doesn't really seem to matter

[53:41] for sake of hypertrophy,

[53:44] when you're really trying

[53:47] Now, it is clear, however

[53:50] that one needs to perform those sets

[53:54] to failure where you can't

[53:57] in good form again or near to failure.

[54:01] And there's all sorts of

[54:03] that's popping up all over the internet.

[54:05] Some of which is scientific,

[54:07] about how you are supposed to perceive

[54:10] how close you were to failure, et cetera.

[54:13] But there are some very

[54:15] that relate to how the

[54:18] that strongly predict

[54:20] that you're performing will

[54:23] So here's how it goes.

[54:24] For individuals that are untrained

[54:27] meaning they have been

[54:31] for anywhere from zero,

[54:35] although for some people, it

[54:37] but those are the so-called beginners.

[54:39] They're sort of untrained.

[54:41] For those people, the

[54:44] to perform enough sets of a given exercise

[54:47] per muscle per week.

[54:50] The same is also true for

[54:52] for one or two years or more.

[54:54] What differs is how many sets to perform

[54:58] depending on whether or not

[55:00] So let's say you're somebody

[55:00] who's been doing some

[55:03] on and off over the years

[55:07] to get serious about

[55:09] or offsetting age related

[55:12] the range of sets to do in

[55:16] to activate these cascades

[55:20] from two, believe it

[55:23] Again, these are sets per week

[55:25] and they don't necessarily

[55:27] in the same weight training session.

[55:28] I will talk about numbers of sessions.

[55:31] So it appears that five sets

[55:37] of the one repetition maximum range,

[55:40] getting close to failure,

[55:44] going to full muscular

[55:47] full muscular failure, but the inability

[55:49] to generate a contraction of the muscle

[55:51] or move the weight in good form.

[55:53] I'll go deeper into that in a moment.

[55:54] But about five sets per

[55:57] just to maintain your muscle.

[55:58] So think about that.

[55:59] If you're somebody who's kind of averse

[56:01] to resistance training,

[56:03] muscle size and strength.

[56:05] Your metabolism will drop.

[56:06] Your posture will get worse.

[56:08] Everything in the context of nerve

[56:10] to muscle conductivity

[56:13] unless you are generating

[56:19] of this 30% to 80% of your one

[56:24] So what this means is

[56:26] who hasn't done a lot of weight training,

[56:27] you need to do at least

[56:31] Now, that's just to maintain.

[56:33] And then there's this huge range

[56:35] that goes all the way up to 15

[56:36] and in some case, 20 sets per week.

[56:38] Now, how many sets you

[56:41] on the intensity of the

[56:45] This is where it gets a

[56:47] but I think nowadays most people agree

[56:50] and Dr. Galpin confirmed

[56:54] with the 10% we discussed

[56:59] of a given workout or

[57:05] should be of the high-intensity sort

[57:07] where one is actually

[57:09] Now I say not true muscular failure

[57:11] because in theory you

[57:14] which is the kind of

[57:15] and then you have the ecentric portion

[57:17] of muscle contraction,

[57:19] And ecentric movements because of the way

[57:21] that muscle fibers lengthen

[57:25] that we talked about before,

[57:26] you're always stronger

[57:28] than you are in lifting it.

[57:31] But the point being that

[57:34] most of your sets should

[57:38] And the reason for that is it

[57:42] of work without fatiguing

[57:46] and depleting the nerve

[57:48] in ways that are detrimental.

[57:50] So we can make this simple.

[57:52] Perform anywhere from 5 to 15 sets

[57:56] of resistance exercise per week,

[57:59] and that's per muscle, and

[58:03] of what your one-repetition maximum.

[58:05] That seems to be the most

[58:08] of offsetting any decline

[58:12] if you're working in the

[58:14] and in increasing muscle strength

[58:18] when you start to get up

[58:21] Now, the caveat to that is everyone varies

[58:24] and muscles vary in terms

[58:28] Depending on how well you

[58:31] of muscles deliberately.

[58:33] And you can actually figure

[58:36] you might take five minutes

[58:36] and just kind of March across your body

[58:38] and mentally try and

[58:40] of muscles in a very deliberate way

[58:43] to the point where you can

[58:45] And you may have to move a limb

[58:46] in order to do this, by the way.

[58:47] I'm not talking about just

[58:50] without moving your wrist.

[58:51] I'm talking about doing

[58:54] in hand or any band or any resistance.

[58:56] If you can generate a

[58:59] using these upper motor neuron

[59:00] to lower motor neuron pathways to muscle,

[59:04] you might think, well I

[59:09] But actually, the opposite is true.

[59:12] If you can generate high-intensity

[59:15] using your brain, using your neurons,

[59:17] it will take fewer sets in

[59:22] to maintain itself and

[59:25] in order to grow or get stronger.

[59:28] So the more efficient you are

[59:32] remember, Henneman's size principle

[59:34] the recruit men have more motor units

[59:36] which isn't just muscles,

[59:37] it's nerve to muscle connections.

[59:39] The better you are at doing that, the more

[59:41] you will recruit these so-called

[59:43] the ones that are hard to get to,

[59:45] the more you will kick

[59:47] within muscle that stimulate

[59:52] So if you have muscles that

[59:56] it's going to take more sets

[59:58] in order to stimulate the desired effect

[1:00:01] in those muscles not fewer.

[1:00:04] If you have muscles that you are very good

[1:00:06] at generating force within,

[1:00:09] Now, how many sets you are

[1:00:12] it's going to depend for

[1:00:14] like 50% of your one-repetition maximum,

[1:00:17] because you're doing a lot of repetitions,

[1:00:19] you might find that

[1:00:22] will maintain the muscle.

[1:00:24] You might decide to do that once

[1:00:25] at one point in the week

[1:00:28] So if you're going for 10 sets a week

[1:00:29] you can divide that among two sessions.

[1:00:31] You could do that all in one session.

[1:00:33] The data really show it doesn't matter.

[1:00:36] There are some differences in terms of

[1:00:39] whether or not you're trying

[1:00:42] within a workout or whether or not

[1:00:43] you want to spread that out.

[1:00:44] But in general, resistance workouts

[1:00:46] of any kind tend to be best favored

[1:00:48] by workouts that are somewhere

[1:00:50] between 45 minutes and 60 minutes.

[1:00:53] And generally not longer than 60 minutes

[1:00:55] because that's when all

[1:00:58] and some of the inflammatory

[1:01:00] to create a situation in

[1:01:04] that's not so great for you.

[1:01:05] So it's not a hard and fast rule.

[1:01:07] The ax doesn't drop at 60 minutes

[1:01:10] but it's pretty clear

[1:01:12] to 15 sets per week, whether

[1:01:15] or whether that's divided

[1:01:18] is really what's going

[1:01:19] And please do keep in mind

[1:01:22] and the recruitment of motor units.

[1:01:24] And remember the better you are

[1:01:25] at contracting particular muscles

[1:01:27] in an isolating those muscles,

[1:01:28] the fewer sets likely you need to do

[1:01:30] in order to get the desired effect.

[1:01:33] Now, what about people who

[1:01:35] If you're somebody who's been doing

[1:01:36] weight training for a while,

[1:01:40] that more volume can be

[1:01:43] that you are very

[1:01:47] Now, the curve on this, the graph on this

[1:01:50] begins again at about five sets per week

[1:01:52] for maintaining a given muscle group,

[1:01:54] and extends all the way out

[1:01:59] However, there are individuals

[1:02:03] can generate so much force.

[1:02:05] They're so good at training muscles

[1:02:07] that they can generate so

[1:02:10] or six or eight sets that

[1:02:14] of work is actually going

[1:02:16] So everyone needs to

[1:02:19] First of all, how often you're willing

[1:02:20] to do resistance exercise of any kind.

[1:02:23] And again, it doesn't

[1:02:25] or weights or body weight.

[1:02:26] For instance, if you're

[1:02:29] unless you are very strong

[1:02:32] You're just using something

[1:02:34] Or if you're doing pushups,

[1:02:38] in that 30% to 80% of your

[1:02:41] It doesn't necessarily mean

[1:02:42] that you have to be moving

[1:02:46] So the purpose here is to figure out

[1:02:49] what muscles you're trying to train.

[1:02:50] That's an issue that we'll

[1:02:53] And then it does appear that somewhere

[1:02:54] between five and 15 sets

[1:03:00] the thing that's going

[1:03:01] Now, this is based on a

[1:03:03] that was done by Andy

[1:03:05] Brad Schoenfeld and colleagues

[1:03:11] There's a huge group of people

[1:03:13] out there doing exercise

[1:03:16] of them that are linking them

[1:03:20] that don't just pertain to athletes.

[1:03:22] So that's mainly what

[1:03:24] And surely there will be exceptions.

[1:03:26] Now, if you are going to

[1:03:30] you're not going to do

[1:03:32] for a given muscle group in one session,

[1:03:34] then of course, it's imperative

[1:03:36] that the muscles recover

[1:03:38] And we are going to talk about recovery

[1:03:40] both at the systemic level,

[1:03:43] and at the local level the nerve to muscle

[1:03:46] and local even muscle level.

[1:03:47] We'll talk about that in about 10 minutes

[1:03:49] when we talk about recovery.

[1:03:51] I do want to mention

[1:03:53] which is that everything

[1:03:55] it has to do with full range of motion.

[1:03:58] And you might ask, well, what

[1:04:02] This is actually turns out

[1:04:03] to be a really interesting dataset

[1:04:05] for generating explosiveness and speed.

[1:04:08] So for sprinters or throwing sports,

[1:04:10] or for people that want to

[1:04:13] it does appear that

[1:04:16] as fast as you safely can,

[1:04:20] to heavy loads, can increase

[1:04:24] And most of that effect is

[1:04:30] It's not from changes in the muscle.

[1:04:31] It's from changes in the way

[1:04:34] communicate with the lower motor neurons

[1:04:37] and generating a pathway, a

[1:04:41] that is very efficient at

[1:04:44] which are the electricity within neurons

[1:04:46] to trigger the muscle.

[1:04:47] Now, of course there

[1:04:48] from nerve to muscle

[1:04:49] but the takeaway from that

[1:04:53] is that if you want to get faster,

[1:04:56] yes, it can be beneficial to get stronger.

[1:04:59] But if you want to dedicate

[1:05:03] to jumping higher, to running

[1:05:09] and these sorts of things that

[1:05:13] with increasing speed is

[1:05:16] On the flip side of that

[1:05:17] for people that want to get stronger,

[1:05:19] it appears that the

[1:05:22] as things get harder is a key parameter

[1:05:24] in recruiting those high

[1:05:27] So let me phrase that a

[1:05:29] Think about a set in the gym

[1:05:31] or think about a set of

[1:05:33] Initially you can move

[1:05:36] If you want to generate hypertrophy,

[1:05:38] the goal really is not

[1:05:40] but to isolate the muscle

[1:05:41] and therefore not to use momentum rather

[1:05:43] than lift weights, as they

[1:05:46] If you want to get stronger,

[1:05:48] you're going to be

[1:05:49] over more muscles and more

[1:05:52] For generating explosiveness and speed,

[1:05:55] it's very clear that learning

[1:05:59] and to move heavy or

[1:06:03] is going to be beneficial

[1:06:04] that you train the motor neurons.

[1:06:07] And of course changes in the muscle.

[1:06:09] But this could look different

[1:06:12] And obviously you want

[1:06:14] If you're injured, you're

[1:06:15] to train at all for sport

[1:06:19] And so what this would involve

[1:06:23] of a one-repetition maximum,

[1:06:26] moving that as quickly as one

[1:06:30] And certainly not going to failure

[1:06:32] because as you approach failure,

[1:06:33] the inability to move the

[1:06:36] the weight inevitably slows down.

[1:06:38] In fact, there are a lot

[1:06:41] that are focused on informing people

[1:06:43] of how quickly the bar

[1:06:46] I saw an advertisement

[1:06:48] There are things that

[1:06:51] that will literally speak to you

[1:06:52] as you're doing a set and inform you

[1:06:54] whether or not you're moving

[1:06:58] than you were at the beginning.

[1:06:59] And trying to hone in on

[1:07:02] In talking to these experts

[1:07:05] it does appear that for

[1:07:08] as long as you're not

[1:07:11] that you start to distribute the effort

[1:07:12] to lots of other muscles,

[1:07:15] it doesn't really matter

[1:07:20] the motor units that you

[1:07:23] of neurons that you recruit

[1:07:24] and the number of muscle

[1:07:26] these high threshold muscle

[1:07:28] And so it's really only

[1:07:31] that you really need to be concerned about

[1:07:34] how quickly the weight is slowing down.

[1:07:37] However, if you're trying to

[1:07:39] and generate more speed and

[1:07:44] things of that sort, you never

[1:07:47] or get to a portion of the set

[1:07:49] where you're moving the

[1:07:51] And I'm sure as I say that some

[1:07:52] of the exercise physiologists

[1:07:53] and advanced trainers out there will come

[1:07:55] after me with pitchforks, which is fine.

[1:07:57] I'd love to see the literature that shows

[1:07:58] that low gear slow movements

[1:08:01] can indeed improve explosiveness.

[1:08:04] And that may in fact be the case,

[1:08:06] but the data that I was able

[1:08:09] as I described just a moment ago.

[1:08:11] So as you're probably

[1:08:12] to customize a resistance practice

[1:08:16] for your particular needs and goals.

[1:08:18] And I certainly am not

[1:08:21] that people periodize their training.

[1:08:23] That they do things from anywhere

[1:08:24] from one month to six months,

[1:08:26] and to make modifications as they go.

[1:08:29] Because the nervous system in particular

[1:08:31] the neuromuscular system

[1:08:34] at the beginning of training.

[1:08:35] In fact, some of the

[1:08:37] when they first embrace or

[1:08:43] can be very remarkable, but

[1:08:46] So we've talked about a few principles.

[1:08:47] The fact that you need

[1:08:49] you need at least five sets to maintain

[1:08:51] and you probably need about

[1:08:53] in order to improve muscle.

[1:08:55] That moving weights of moderate

[1:08:56] to moderately heavy weight quickly

[1:08:59] is going to be best for explosiveness.

[1:09:00] The isolating muscles and

[1:09:04] something that you can test by just

[1:09:06] when you're outside the training session,

[1:09:08] seeing whether or not you

[1:09:11] will tell you your capacity

[1:09:15] or to engage strength

[1:09:18] That your ability to

[1:09:21] inversely related to the number

[1:09:24] in order to isolate and

[1:09:27] And there are some other

[1:09:30] the whole process of building

[1:09:34] making them more efficient

[1:09:36] more strength and hypertrophy.

[1:09:39] One of them I loath to say I was told

[1:09:43] is in between set contractions.

[1:09:46] The other name for this is the people

[1:09:48] in the gym does typically

[1:09:52] flexing their muscles in between sets.

[1:09:54] And indeed the research supports the fact

[1:09:57] that contractions have about 30 seconds

[1:10:00] in between the actual work sets,

[1:10:02] they're not going to

[1:10:05] on the work sets, if anything

[1:10:06] they're going to compromise them.

[1:10:07] But those hard contractions

[1:10:10] for a variety of reasons related

[1:10:14] as well as what we talked about before

[1:10:16] which are stress, tension, and damage,

[1:10:18] they seem to improve

[1:10:20] and the nerve to muscle contraction

[1:10:22] in ways that facilitate hypertrophy.

[1:10:24] In other words, if you

[1:10:27] in between sets in the gym,

[1:10:28] provided that they're

[1:10:31] and provided it's one that

[1:10:35] not one of these people

[1:10:36] that always skips leg day type of people.

[1:10:38] These people are highly asymmetric

[1:10:40] although that's up to them,

[1:10:42] that process of flexing

[1:10:46] to improve the nerve to muscle connection

[1:10:48] and enhance hypertrophy.

[1:10:51] And I say I was low to say it

[1:10:54] it seems like the end of

[1:10:58] sort of like the 11th rep of every set.

[1:11:00] I like to joke.

[1:11:01] It seems like very few people

[1:11:03] into the gym and doing a workout

[1:11:05] without taking a picture of themselves,

[1:11:07] which I think is fine

[1:11:10] Although I must say that

[1:11:13] and even the recreational

[1:11:15] who seem to get the most

[1:11:17] and who also seem to get the most out

[1:11:19] of other aspects of their life,

[1:11:20] seem to be able to control

[1:11:22] both in the gym and outside of the gym.

[1:11:24] But that's more of an

[1:11:26] In an earlier episode,

[1:11:28] I talked about estrogen and testosterone.

[1:11:30] And during that discussion, I talked about

[1:11:32] the use of resistance

[1:11:35] for increasing testosterone,

[1:11:39] And indeed that is a powerful

[1:11:44] And indeed it's mediated by the

[1:11:48] We talked about that in

[1:11:51] I just want to briefly

[1:11:53] since it's distinctly different

[1:11:54] from the other protocols

[1:11:57] The protocols I've talked

[1:11:59] of explosive movements or of

[1:12:04] provided the training

[1:12:07] will cause increases in serum testosterone

[1:12:10] that's been shown over and over again.

[1:12:12] And if the session extends

[1:12:16] and is of sufficiently

[1:12:19] testosterone levels will start to drop

[1:12:22] and cortisol levels will go up

[1:12:24] in ways that can be

[1:12:26] and the goals of the training.

[1:12:28] But that's different than training

[1:12:31] that's specifically geared

[1:12:34] Duncan French, who's one of the directors

[1:12:36] of the UFC Performance Center,

[1:12:38] when he was a graduate student

[1:12:40] at University of Connecticut

[1:12:43] He and his colleagues found

[1:12:46] for stimulating testosterone release

[1:12:48] which is something that

[1:12:50] for a variety of reasons.

[1:12:52] And that involved doing

[1:12:58] even if it requires lightening the weight

[1:13:02] on one set to the next,

[1:13:06] 120 seconds rest in between sets.

[1:13:08] Which if you think of about

[1:13:12] and is pretty darn hard work.

[1:13:15] Now, what's interesting is that

[1:13:16] there's a very limited threshold

[1:13:18] for increasing testosterone.

[1:13:20] That protocol of six sets

[1:13:25] to these big increases

[1:13:28] But if people did 10 sets of 10

[1:13:29] so just four more repetitions per set,

[1:13:32] then testosterone did not increase.

[1:13:34] In fact, you got more of this

[1:13:35] catabolic cortisol like pathway.

[1:13:37] You get other benefits from this

[1:13:39] so-called 10 sets of 10 protocol,

[1:13:41] but not the testosterone increase

[1:13:43] and maybe even reductions in testosterone.

[1:13:45] Now, it's important to point out that

[1:13:47] that six sets of 10 was done

[1:13:50] So things like squats,

[1:13:53] or things of that sort.

[1:13:54] And those were done as single sessions

[1:13:56] not in concert with a bunch

[1:14:00] if athletes are doing

[1:14:03] why they couldn't also do other types

[1:14:04] of training elsewhere in the week.

[1:14:06] I asked Duncan about this

[1:14:08] that done twice a week

[1:14:11] that anyone could do that

[1:14:14] and still maintain this

[1:14:16] It's a very interesting protocol

[1:14:18] because as a neuroscientist, it's amazing

[1:14:22] to me that six sets of 10

[1:14:28] causes a distinctly different result

[1:14:30] in terms of hormone output

[1:14:32] than 10 sets of 10 of

[1:14:34] And it speaks to the

[1:14:38] to muscle connections

[1:14:42] of your entire system.

[1:14:44] If there's a theme that I really

[1:14:46] is that weight training or

[1:14:50] is really used for

[1:14:53] 10% of training done where

[1:14:56] which means lactate will be present

[1:14:57] and sending signals to your brain,

[1:14:59] and your heart and your

[1:15:01] or isolating muscles

[1:15:05] a kind of a lactate which is

[1:15:10] but that isolation of

[1:15:13] So systemic versus isolated.

[1:15:15] Those are the two general ways

[1:15:17] in which resistance

[1:15:19] So I just wanted to mention

[1:15:21] because it's well supported

[1:15:24] If you were to incorporate that protocol,

[1:15:26] you might ask, well, then can you do any

[1:15:28] other weight training during the week?

[1:15:29] And sure, of course you can

[1:15:32] So let's talk about how you

[1:15:35] How you know if a muscle is recovered

[1:15:37] and how you know if your

[1:15:39] Because recovery is what

[1:15:42] you can come back and do more

[1:15:44] Meaning, I don't know, you

[1:15:48] can you and should you come back

[1:15:49] and do the upper body training day?

[1:15:52] And it dictates whether or

[1:15:55] from session to session at all.

[1:15:57] Before I talk about recovery

[1:15:58] I just want to make sure

[1:16:00] that I was able to extract

[1:16:03] and from my conversation with Dr. Galpin.

[1:16:05] If you're wondering how

[1:16:08] for sake of hypertrophy or strength gains,

[1:16:11] anywhere from a half a

[1:16:14] all the way up to eight

[1:16:16] it doesn't seem to matter.

[1:16:18] Again, if you're thinking

[1:16:20] or building speed, or you're specifically

[1:16:22] using resistance training

[1:16:24] that's a separate matter.

[1:16:25] We talked about explosiveness and speed.

[1:16:27] I'll talk about endurance

[1:16:29] We also talked about in

[1:16:32] the so called selfie effect

[1:16:34] of people flexing a particular muscle,

[1:16:36] isolating a particular

[1:16:39] just want to mention that

[1:16:42] if your goal is performance on sets.

[1:16:44] So moving a particular amount of weight.

[1:16:46] That's actually going to

[1:16:49] that you can move.

[1:16:50] It's going to enhance muscle growth

[1:16:51] and it's going to enhance the nerve

[1:16:53] to muscle isolation of

[1:16:57] So again, that flexing

[1:17:00] to favor hypertrophy, not performance.

[1:17:03] If you're trying to get stronger,

[1:17:06] you're trying to move more weights,

[1:17:07] you're trying to distribute work,

[1:17:09] and you're trying to

[1:17:11] with resistance then flexing between sets

[1:17:13] is absolutely the wrong thing

[1:17:16] you're fatiguing the muscle further.

[1:17:18] Just remaining still or

[1:17:21] has been shown to be beneficial in terms

[1:17:23] of moving some of the

[1:17:25] as well as just recovering between sets.

[1:17:28] Now, how long to recover

[1:17:30] For the testosterone protocol,

[1:17:33] found that it was about

[1:17:35] that really on the clock,

[1:17:38] For hypertrophy and for strength gains,

[1:17:41] it does seem that resting

[1:17:43] or even three or four,

[1:17:47] can be beneficial.

[1:17:48] And if you're interested

[1:17:50] of work that you can do in a given session

[1:17:53] at high capacity at high

[1:17:57] please see the episode that I did

[1:17:58] on cold and performance about

[1:18:02] which is based on the work of my colleague

[1:18:03] Craig Heller in the Biology

[1:18:06] which talks about Palmer Cooling,

[1:18:07] about how you can cool

[1:18:10] through the palms using these

[1:18:14] that are only present in your hands.

[1:18:16] People are now doing this with

[1:18:20] There are a number of

[1:18:21] I talk all about that in that episode.

[1:18:23] It allows you to do more repetitions

[1:18:26] and more work at a given weight over time.

[1:18:29] So rather than getting 10 repetitions

[1:18:31] and then eight and then seven and then six

[1:18:33] through proper use of palmer cooling,

[1:18:35] one can do 10, 10, 10,

[1:18:39] And that's one way that one can accomplish

[1:18:41] higher volume work without having

[1:18:44] to drop the weight considerably.

[1:18:45] So that's where you can

[1:18:48] if that's your goal of getting strong

[1:18:50] and generating some hypertrophy.

[1:18:52] Because as soon as you have

[1:18:56] then you're shifting

[1:18:58] and endurance and less toward

[1:19:01] So check out that episode.

[1:19:03] The last thing besides

[1:19:06] and whether or not

[1:19:08] or whether or not you're really

[1:19:11] is this notion of pre-exhausting muscles.

[1:19:14] It's been shown over and over again

[1:19:16] that for instance, if you

[1:19:20] in a given muscle and really isolate that,

[1:19:22] doing the isolation work

[1:19:25] So this would be leg extensions

[1:19:28] the thing where you sit

[1:19:28] and you extend your toes

[1:19:31] Leg extensions before

[1:19:35] to target that muscle

[1:19:37] And that makes perfectly

[1:19:40] the Henneman's size principle

[1:19:43] It should be obvious why that's the case.

[1:19:44] But of course that's going

[1:19:48] in terms of how much weight you can lift,

[1:19:50] and maybe even the form

[1:19:51] when you move to the

[1:19:53] So you really have to ask

[1:19:56] How good are you at

[1:19:59] Therefore, how many

[1:20:01] How often are you willing to train

[1:20:03] therefore, how many

[1:20:05] in a given session versus

[1:20:07] to distribute across the week?

[1:20:09] Are you aiming for performance?

[1:20:10] Are you going to distribute that work

[1:20:12] across the nervous system and musculature?

[1:20:14] Are you trying to move weights?

[1:20:15] Are you trying to challenge muscles?

[1:20:17] If you're trying to challenge muscles,

[1:20:18] then you really want to focus on things

[1:20:20] like this pre exhausting the isolation

[1:20:22] of a muscle before the compound movement.

[1:20:24] Your performance on compound movements

[1:20:26] will absolutely suffer but your ability

[1:20:29] to isolate that muscle

[1:20:31] through the accumulation of larger myosin,

[1:20:34] those bigger balloons, will benefit.

[1:20:36] And once again, if you're

[1:20:39] than the speed of the

[1:20:42] So how do we know if we've recovered?

[1:20:43] How can we test recovery?

[1:20:45] And this is not just recovery

[1:20:47] this is recovery from running,

[1:20:51] Up until now I've been talking

[1:20:53] more or less in a vacuum.

[1:20:54] I haven't even touched on the fact

[1:20:56] that many people are running

[1:20:57] and they're doing resistance training

[1:20:59] or they're swimming and they're

[1:21:02] It's not simply the case that

[1:21:06] you can just work other muscles.

[1:21:07] Because even if you've

[1:21:11] let's say you have incredible abilities

[1:21:13] to isolate just your

[1:21:17] and you do a workout where

[1:21:19] you do your six sets of intense work

[1:21:21] or maybe use palmer cooling,

[1:21:22] and you're able to do

[1:21:24] and you're done, and that muscle group

[1:21:28] the next day is certainly

[1:21:30] unless you're somebody who's

[1:21:33] or you're enhancing your

[1:21:36] which we'll talk about at the end.

[1:21:38] Well, you can assess systemic recovery

[1:21:41] meaning your nervous system.

[1:21:43] And your nervous system's

[1:21:46] both distributed and isolated

[1:21:51] And fortunately, these

[1:21:54] and two of them are essentially zero cost,

[1:21:57] require no equipment.

[1:21:59] HRV, heart rate variability

[1:22:04] into the forefront of exercise physiology

[1:22:07] and even into the popular discussion.

[1:22:09] I've talked about HRV before.

[1:22:11] How when we exhale, our

[1:22:13] because of the way that our diaphragm

[1:22:14] is connected to our heart and to our brain

[1:22:16] and the way our brain is

[1:22:18] When we inhale our heart rate speeds up

[1:22:21] and that is the basis of

[1:22:24] Heart rate variability is good.

[1:22:26] It means that you're breathing properly,

[1:22:28] and when I say it's good it means

[1:22:30] you want a lot of heart rate variability.

[1:22:32] You don't want a heart rate that is high

[1:22:34] or low consistently over time.

[1:22:37] That might come as a bit

[1:22:39] endurance athletes,

[1:22:41] to accomplish your endurance

[1:22:44] to really hit that nice sweet spot

[1:22:45] where you're breathing rhythmically,

[1:22:47] your heart rate's going rhythmically.

[1:22:48] You're in that steady heart rate,

[1:22:49] and then away from exercise,

[1:22:51] you have a nice low

[1:22:53] Well, nice low heart rate isn't

[1:22:56] Turns out the introducing bouts

[1:22:58] of increasing your heart

[1:23:00] and even through your waking day,

[1:23:02] through stressful events

[1:23:04] is beneficial.

[1:23:06] A good nerve to heart system benefits

[1:23:10] from being able to increase heart rate

[1:23:12] and decrease heart rate.

[1:23:13] Heart rate variability is good.

[1:23:15] So you don't want high heart rate,

[1:23:17] you don't want low

[1:23:20] But heart rate variability is difficult

[1:23:21] for a lot of people to measure.

[1:23:23] There are some devices that

[1:23:25] Various watches and devices.

[1:23:27] There are more devices becoming

[1:23:31] Hopefully soon, some that are integrated

[1:23:32] with your phone that involve no contact

[1:23:34] or anything on your body.

[1:23:36] But those do carry some costs

[1:23:41] The measures of heart rate

[1:23:44] while in movement are still in that phase

[1:23:47] I would say of technology development

[1:23:49] where everyone isn't using

[1:23:52] There are two measures however,

[1:23:53] whether or not you

[1:23:55] first thing in the

[1:23:57] maybe after five, 10 minutes, if you like,

[1:23:59] but ideally right when you wake up

[1:24:02] in order to assess how

[1:24:04] and therefore whether

[1:24:06] your whole system at all that day.

[1:24:09] The first one his grip strength.

[1:24:11] Grip strength, the

[1:24:15] at the level of squeezing the fist

[1:24:17] or squeezing down on something,

[1:24:19] might seem like kind of a trivial way

[1:24:21] to assess recovery but

[1:24:23] to your ability to use

[1:24:26] to control your lower motor neurons

[1:24:28] and to generate isolated force.

[1:24:30] So that's really what you're

[1:24:33] Some people will use

[1:24:37] or Costello has this toy

[1:24:41] and it's this hard rubber.

[1:24:43] And I've tried this before.

[1:24:45] If I've been working really

[1:24:47] or I've been training a lot

[1:24:48] any one or combination of

[1:24:51] I can't actually squeeze that thing down

[1:24:53] as much as I can Costello

[1:24:55] with like a 24 inch neck

[1:24:57] even though he's never touched a weight

[1:24:59] somehow he can just

[1:25:01] and he can turn it into

[1:25:03] and he likes to chuckle while

[1:25:06] But on a good day, I

[1:25:07] so that I eliminate the hole

[1:25:10] You can also take a floor

[1:25:16] and see how much force you can generate.

[1:25:18] I would do that as a baseline to establish

[1:25:20] what you can do when you're well rested.

[1:25:23] And then if you do that in the morning,

[1:25:24] you can see whether or not you're able

[1:25:25] to generate the same amount of force

[1:25:27] or you could use over the

[1:25:29] A lot of this is very subjective

[1:25:30] with a scale you're

[1:25:32] whether or not you can generate

[1:25:35] If you start seeing a 10% or

[1:25:39] that's concerning, it

[1:25:41] your nervous system as a whole

[1:25:43] it's not necessarily

[1:25:46] from nerve to muscle

[1:25:49] of rewiring themselves in

[1:25:52] And you might think, well, I

[1:25:55] Why am I having a hard time doing this

[1:25:56] for a completely different muscle group?

[1:25:58] It doesn't make any sense.

[1:25:59] But there's something about

[1:26:01] to lower motor neuron pathway generally

[1:26:04] that allows you to use

[1:26:06] as a kind of a thermometer, if you will

[1:26:09] of your ability to recover.

[1:26:11] So look for your ability

[1:26:13] when you first wake up.

[1:26:14] It's not going to be as

[1:26:17] after a cup of coffee and a couple meals

[1:26:19] but the point isn't performance overall,

[1:26:22] the point is to assess whether or not

[1:26:24] you're getting better, worse

[1:26:27] The other one that's really terrific

[1:26:28] and the Andy Galpin's group is using.

[1:26:30] And I'm delighted about

[1:26:32] to something that my lab is

[1:26:34] is carbon dioxide tolerance.

[1:26:36] So this is a really interesting tool

[1:26:38] that endurance athletes, strength athletes

[1:26:41] I think can all benefit from.

[1:26:43] In fact athletes and people of all kinds.

[1:26:45] Even if you're not an athlete,

[1:26:46] even if you're not exercising at all,

[1:26:48] there's a good question of

[1:26:50] as a whole is doing okay or not.

[1:26:53] We rely on the thermometer.

[1:26:54] Do we have a fever or not?

[1:26:56] We rely on subjective things.

[1:26:58] Do I feel good or not?

[1:26:59] Am I digesting well or not?

[1:27:00] Those are all subjective.

[1:27:02] The carbon dioxide tolerance test is,

[1:27:06] its objective in that it

[1:27:09] to engage the so-called

[1:27:12] of your nervous system

[1:27:14] of your nervous system.

[1:27:15] And it measures your ability

[1:27:18] a particular skeletal muscle,

[1:27:21] So here's how you do the

[1:27:24] You wake up in the morning.

[1:27:25] If you have to use the

[1:27:27] but try and stay away from your phone.

[1:27:30] If you have your phone,

[1:27:32] go to the timer or use a

[1:27:35] of measuring time, stay off social media

[1:27:39] for just a few seconds.

[1:27:40] It'll be okay.

[1:27:41] And what you're going to do

[1:27:43] through your nose as deeply as you can,

[1:27:45] you can do this lying

[1:27:49] inhale through your nose

[1:27:54] So that's one.

[1:27:54] You're going to repeat that four times.

[1:27:57] So inhale, exhale, inhale, exhale

[1:28:02] inhale, exhale, inhale, exhale four times.

[1:28:05] And ideally you're

[1:28:07] and you're exhaling through the mouth.

[1:28:09] That's just the beginning

[1:28:10] of this carbon dioxide tolerance test.

[1:28:13] Then you take a fifth inhale

[1:28:15] as deep as you can through your nose.

[1:28:17] Fill your lungs as much as you can,

[1:28:19] and if you can try and expand

[1:28:22] make your stomach go

[1:28:23] that means that your

[1:28:26] So you're inhaling as

[1:28:29] Then hit the timer and

[1:28:32] that air as slowly as

[1:28:36] So it looks like you have

[1:28:39] in your mouth and you're letting it go.

[1:28:44] As slowly as you possibly can.

[1:28:47] Measure what we call the

[1:28:50] or discard rate.

[1:28:53] I know you can all sit with lungs empty

[1:28:55] after you eliminate all that

[1:28:59] Don't stop the timer

[1:29:02] with your lungs empty for a while,

[1:29:04] stop the timer when you

[1:29:07] able to exhale any more air.

[1:29:11] So you do inhale, exhale, inhale, exhale,

[1:29:13] inhale, exhale, inhale, exhale slowly.

[1:29:16] I just said it quickly for sake of time

[1:29:18] then you can do this fifth

[1:29:21] and then [deep exhale]

[1:29:24] And I'm not going to do

[1:29:28] And then you're measuring that time.

[1:29:30] Your carbon dioxide discard

[1:29:34] between one second and

[1:29:39] Two minutes would be a heroic

[1:29:43] 30 seconds would be more typical.

[1:29:45] 20 seconds would be fast.

[1:29:47] If your carbon dioxide discard time

[1:29:51] is 20 or 25 seconds or less,

[1:29:55] you are not necessarily recovered

[1:29:58] from your previous days activities.

[1:30:01] There's ways to push through this

[1:30:02] but hold onto that thought for a moment.

[1:30:05] If your carbon oxide

[1:30:07] between about 30 seconds and 60 seconds,

[1:30:12] you are in what we would

[1:30:16] where you are in a position

[1:30:22] And if your carbon dioxide

[1:30:24] between 65 and 120 seconds,

[1:30:28] well then you have almost certainly

[1:30:31] recovered your nervous system.

[1:30:33] I'm not talking about

[1:30:34] but your nervous system is

[1:30:37] And Andy's Lab has great data on this

[1:30:40] as it relates to exercise physiology.

[1:30:41] I think that story should be out

[1:30:43] in the not too distant future.

[1:30:44] My lab has been using

[1:30:47] to look at anxiety and

[1:30:50] So two totally independent projects

[1:30:52] but using the same measure.

[1:30:54] So you've got HRV, which

[1:30:58] You've got grip strength,

[1:30:59] which you can assess subjectively

[1:31:02] or you can use a floor scale

[1:31:04] and now you have carbon dioxide tolerance.

[1:31:06] You want to do this in the

[1:31:09] and keep track just write

[1:31:12] or maybe just keep tracking your mind

[1:31:13] of your carbon oxide discard time.

[1:31:15] If you find that your

[1:31:19] even if they're in the

[1:31:22] but normally you can do

[1:31:26] If they're starting to drop

[1:31:30] you're veering in the

[1:31:33] And I'm really keen on this tool

[1:31:35] because everybody has

[1:31:38] Some people are eating really

[1:31:41] Some people have minimal stress

[1:31:42] or can buffer stress really well.

[1:31:44] Other people they dissolve

[1:31:48] if they read one text message

[1:31:53] And I realize, and I

[1:31:55] I realize people have

[1:31:57] and demand in their life.

[1:31:58] It's just to to prescribe

[1:32:02] that says, okay, yes

[1:32:03] and this is exactly what you should do.

[1:32:05] No, you shouldn't.

[1:32:06] Use carbon dioxide discard rate because a,

[1:32:08] it's valuable, it's informative.

[1:32:10] b, it's zero cost and c,

[1:32:15] it's something you can

[1:32:17] And that's really the key.

[1:32:18] And I'd be remiss if I didn't say

[1:32:21] that what carbon dioxide

[1:32:25] is your ability to mechanically

[1:32:28] certainly that's one aspect of it,

[1:32:30] but that relates in a very

[1:32:33] to put the brake on your stress system.

[1:32:36] To engage the so-called parasympathetic

[1:32:39] or calming arm of your

[1:32:41] And another thing that Andy

[1:32:45] is at the offset of

[1:32:49] after your weight training session,

[1:32:50] maybe even after your plyometrics session,

[1:32:53] we didn't really talk

[1:32:55] and that sort of thing.

[1:32:57] Maybe we'll talk about

[1:32:59] But they and other groups,

[1:33:04] and other groups that are very interested

[1:33:06] in physical performance are using a tool

[1:33:10] where they deliberately disengaged

[1:33:12] for five minutes at the end of training.

[1:33:14] They deliberately engage this

[1:33:18] of the nervous system.

[1:33:19] And you can do that through

[1:33:22] I'm a big fan of respiration tools

[1:33:24] 'cause they're always available to you.

[1:33:25] Your breathing is always there.

[1:33:27] I talk about some of these

[1:33:29] but you could use things like

[1:33:32] at the end of a training session.

[1:33:34] You could do 10 physiological size,

[1:33:37] double inhales through the

[1:33:40] that will definitely engage the

[1:33:41] parasympathetic nervous

[1:33:44] So rather than finish

[1:33:46] and then just hop onto your phone,

[1:33:49] serious athletes and people

[1:33:52] initiate that recovery at the

[1:33:56] and they start to kickstart

[1:34:00] and they measure CO2

[1:34:02] So there are several

[1:34:04] In fact, I know several

[1:34:07] with them that are using

[1:34:11] in order to recover their nervous system

[1:34:12] and maintain nerve to

[1:34:16] Maintain focus throughout

[1:34:18] enhance their focus by doing

[1:34:22] So double inhale, exhale in between sets.

[1:34:25] So they're getting very

[1:34:27] about their strength work

[1:34:29] muscle isolation work during their sets.

[1:34:31] And then in between sets,

[1:34:33] disengaging the nervous system,

[1:34:35] and then they're re-engaging it again.

[1:34:37] So I just wanted to emphasize that.

[1:34:39] So recovery is a complex process.

[1:34:41] It's got a lot of things

[1:34:43] but the CO2 tolerance set

[1:34:46] Now, another tool for recovery

[1:34:47] that people are very excited about

[1:34:49] is the use of cold and the ice bath.

[1:34:51] And this is important.

[1:34:53] If you are somebody who uses

[1:34:56] or ice bath, or jumping

[1:34:59] whatever it is that used to generate cold

[1:35:01] as a recovery tool, you should be aware

[1:35:03] that there are data

[1:35:05] if your goal is recovery

[1:35:09] using cold within the four

[1:35:13] I'm not talking about

[1:35:14] about whole body cooling or

[1:35:17] Yes, it will reduce inflammation.

[1:35:19] Yes, it will reduce the amount

[1:35:21] of delayed on muscle soreness one readout

[1:35:24] of how intense or damaging

[1:35:27] not the only readout,

[1:35:28] but it does seem to interfere with some

[1:35:30] of the things like mTOR pathways,

[1:35:32] the mammalian target of rapamycin pathway

[1:35:34] and other pathways

[1:35:38] that promote muscle

[1:35:41] Remember, stress, tension, and damage

[1:35:43] or the stimulus for nerve to

[1:35:46] and for muscles to get

[1:35:49] And so if you're getting into

[1:35:52] or taking a really cold shower

[1:35:53] after doing resistance training,

[1:35:55] you are likely short-circuiting

[1:35:58] that you're trying to create.

[1:35:59] Now, athletes who are

[1:36:03] so that they can get back

[1:36:06] or let's say you're

[1:36:07] want to gain much strength or hypertrophy

[1:36:12] and you're mainly focused on endurance

[1:36:13] and you want to do more endurance work

[1:36:15] and you've been weight training,

[1:36:16] well then exposing yourself

[1:36:19] but you're not going to

[1:36:21] from the resistance training.

[1:36:23] In other words, cold

[1:36:25] seems to short circuit

[1:36:27] of that resistance training.

[1:36:29] There are some other things

[1:36:30] that can short circuit the benefits

[1:36:31] of resistance training as well.

[1:36:34] One of those is anti-histamines.

[1:36:37] Some interesting data

[1:36:38] I believe it was in

[1:36:41] that showed that

[1:36:46] of the benefits of cardiovascular exercise

[1:36:48] of endurance type work

[1:36:51] of fairly long duration

[1:36:53] as well as inhibit some of

[1:36:56] with resistance training.

[1:36:59] Remember, it resistance

[1:37:01] that's a stimulus for stress

[1:37:04] and the adaptation to that

[1:37:07] That you can run further, faster,

[1:37:08] lift more weight, hypertrophy

[1:37:12] So anti-histamines can be a problem.

[1:37:14] Obviously don't compromise your ability

[1:37:16] to breathe completely, but

[1:37:19] by blocking what are called

[1:37:22] Mast cells are really interesting cells

[1:37:24] that we'll talk about in our

[1:37:27] They travel in the bloodstream

[1:37:29] and these little packets that burst open

[1:37:31] it sites of inflammation.

[1:37:33] Muscle damage and inflammation is a signal

[1:37:36] that something needs to change.

[1:37:37] And so taking it to histamines

[1:37:41] some of that inflammatory process.

[1:37:42] So you actually want inflammation

[1:37:44] during and immediately after a workout,

[1:37:46] then you want to bring

[1:37:48] and I'll mention how to do that.

[1:37:50] The other thing are non-steroid

[1:37:52] you know their trade names.

[1:37:54] These are painkillers

[1:37:56] Those as I've mentioned

[1:37:58] can interfere with the

[1:38:01] and the benefits of resistance training.

[1:38:04] In addition to that,

[1:38:06] and pain is a very good signal

[1:38:09] that you might be doing something wrong.

[1:38:11] And so while nobody likes to be in pain,

[1:38:13] I suppose there are probably

[1:38:14] like to be in pain, but

[1:38:16] but nobody likes to be in pain.

[1:38:18] The non-steroid

[1:38:20] as they're called, and

[1:38:23] to prevent a lot of the gains

[1:38:25] the improvements in

[1:38:28] that people are specifically

[1:38:31] So be cautious about your use

[1:38:33] of non-steroid anti-inflammatory drugs

[1:38:35] especially within the four hours preceding

[1:38:38] or the four hours following exercise.

[1:38:41] So I hope you're starting

[1:38:43] In order to change the

[1:38:46] in ways that will better serve you,

[1:38:47] you need a stressor

[1:38:51] which particular stressor

[1:38:54] But that stressor is almost always going

[1:38:57] to be associated with inflammation,

[1:38:59] and then after the

[1:39:01] and get into a state of

[1:39:03] And that's why you would

[1:39:07] non sleep depressed which we

[1:39:09] or perhaps you would use the hypnosis app

[1:39:12] that we've talked about before

[1:39:16] There's a great app for

[1:39:20] or the physiological side

[1:39:24] to calm down after training.

[1:39:27] There are also tools that one

[1:39:30] at a kind of foundational

[1:39:33] And these are tools that I've talked

[1:39:35] about many times before, but

[1:39:39] The kind of Golden Three

[1:39:42] and the ones that he recommends are

[1:39:43] sufficient omega-3s again,

[1:39:46] through diet, through whole food intake

[1:39:48] or through supplementation or both.

[1:39:50] So in general, getting

[1:39:52] of EPA per day to keep

[1:39:57] Vitamin D and in some

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